http://www.imunologie.cz/pdf/brezen/6.pdfFound this pdf file with the following excerpt:
"Regarding the supplement MSM (Methylsulfonylmethane), Dr. Cheney stated
"I really like it. It's wonderful stuff." He recommended the book The
Miracle of MSM: The Natural Solution for Pain
<http://virtualhometown.com/dfwcfids/books/index.html> by Stanley Jacob,
William Regelson & Martin Zucker. He said, "Great book. Everything you'd
ever want to know about MSM, written by a physician who's used it for 30
years in his patient population."
Dr. Cheney described five benefits of MSM.
(1) "MSM itself has the toxicity of water - it's non-toxic. But it's a
very potent detoxifier. If you take too much MSM, you can mobilize too
many toxins too quickly. It can even mobilize heavy metals, so you have
to be cautious about the dose. Start low and go slow - work up gradually
to the therapeutic dose, which is 6 to 9 grams a day. Most CFIDS patients
can work up to 6 gms a day, but from there it can be a rocky road."
(2) "MSM is a very potent anti-yeast medication. It causes yeast to blow
up. Well, basically they melt. Their cell walls are destroyed. Again, you
see herxheimer reactions if the dose is too high."
(3) "Pain relief from MSM can be significant, particularly at 6 to 9 gms
a day. This applies to most any pain, because most pain is toxicity
related. Some of the pain relief accounts are pretty impressive. It's
typical to hear at 6 gms, nothing, 8 gms, no relief, then suddenly at 10
gms the pain is gone. There seems to be a threshold you have to reach and
then boom. The threshold will vary from person to person. I encourage
patients to work gradually up to 9 gms. If the pain still has not
resolved, I may try to push some patients to 12 gms. I always get a
little bit concerned though, when they get to 12 gms because of one
patient's experience, which I'll tell you about."
(4) "MSM also helps allergies. The mucous barrier is a sulfur barrier,
and the sulfur binds to allergens and keeps them away from your nasal and
sinus mucosa so you don't get allergies."
(5) "Another reason for CFIDS patients to take MSM is that if you measure
sulfur levels in their blood and urine, most patients are usually very
low. Patients get sulfur depletion very quickly trying to cope with the
toxicity of this illness."
Dr. Cheney had one patient who decided on his own to start with 12 grams
of MSM a day. About a week into the treatment he had what Cheney called
"sudden spontaneous detox". He was extremely ill with diarrhea, vomiting
and flu-like symptoms. He also experienced what Cheney referred to as
"suicidal ideation" - he wanted to kill himself. The episode lasted
almost 12 hours and then abruptly stopped. The patient then felt much
better. Cheney believes that the suicidal urges were the result of toxins
that had been mobilized by the MSM and carried to the brain before being
eliminated. The toxins destabilized him psychologically for a time.
Obviously, this is very dangerous and definitely to be avoided. Start
with a low dose and advance slowly. Cheney has never had a patient who
gradually worked up to 12 grams experience an episode like this, but he
warns patients to be very cautious with the higher doses.
Cheney stressed the importance of buying a pharmaceutical grade MSM. As
already mentioned, sulfur binds to toxins, which makes it a very potent
and effective detoxifier. However, it also means that if manufactured in
a non-sterile environment, it will pick up whatever is in the
environment. Think of it as a sponge for toxins. If itÌs made in a garage
in Mexico, it will absorb the toxins in the garage. MSM can be among the
most toxic supplements on the market if itÌs exposed to toxic materials
during production..."
Nic